Volt akinek a magzata hydrops betegség miatt halt meg a 24. hét előtt (vagy után)? Kiderült, hogy mi okozta ezt a betegséget?

Classification and causes[edit]

Hydrops fetalis usually stems from fetal anemia, when the heart needs to pump a much greater volume of blood to deliver the same amount of oxygen. This anemia can have either an immune or non-immune cause. Non-immune hydrops can also be unrelated to anemia, for example if a fetal tumor or congenital cystic adenomatoid malformation increases the demand for blood flow.[citation needed] The increased demand for cardiac output leads to heart failure, and corresponding edema.

Immune causes[edit]

Rh disease is a cause for immune mediated hydrops fetalis; however, owing to preventative methods developed in the 1970s Rh disease has markedly declined. Rh disease can be prevented by administration of anti-D IgG (Rho(D) Immune Globulin) injections to RhD-negative mothers during pregnancy and/or within 72 hours of the delivery. However a small percentage of pregnant mothers are still susceptible to Rh disease even after having been administered anti-D IgG (Rho(D) Immune Globulin)

Non-Immune causes[edit]

The non-immune form of hydrops fetalis has many causes including:

Iron deficiency anemia

Paroxysmal supraventricular tachycardia resulting in heart failure

Deficiency of the enzyme beta-glucuronidase. This enzyme deficiency is the cause of the lysosomal storage disease called Mucopolysaccharidosis Type VII.

Congenital disorders of glycosylation

Parvovirus B19 (Fifth Disease) infection of the pregnant woman.

Cytomegalovirus in mother.

Maternal syphilis and maternal diabetes mellitus

α thalassemia can also cause hydrops fetalis when all four of the genetic loci for α globin are deleted or affected by mutation. This is termed Hb Barts (consists of y-4 tetramers).

Uncommonly, Niemann-Pick Disease Type C (NPC) and Gaucher Disease type 2 can present with hydrops fetalis.

Turner Syndrome

Tumors,[3] the most common type of fetal tumor being teratoma, particularly a sacrococcygeal teratoma.

Twin-twin transfusion syndrome in monochorionic pregnancy (hydrops affects the recipient twin)

Maternal hyperthyroidism

fetal cardiac defects and skeletal defects

#1 !Köszönjük Emese!

Ez magyar nyelvű oldal,légyszi magyarul írj!